From embryo to maturity

From Prurience to Maturity

Nuclear forensic science—From cradle to maturity

Since the beginning of the 1990s, when the first seizures of nuclear material were reported, the IAEA recorded more than 800 cases of illicit rafficking of nuclear or other radioactive materials. Despite the decreasing frequency of seizures involving nuclear materials (i.e. uranium or lutonium), the issue continues to attract public attention and is a reason for concern due to the hazard associ...

I–Xe dating: From adolescence to maturity

The I–Xe chronometer is based upon decay of now-extinct I where the ratio of accumulated daughter Xe to stable I reflects the iodine isotopic ratio at closure of the host mineral. Since none of the parent remains, I–Xe is by nature a relative chronometer but, when referenced by a standard mineral of known age, the I–Xe system becomes an absolute chronometer reflecting true closure times. Most i...

Tendon-to-bone attachment: from development to maturity.

The attachment between tendon and bone occurs across a complex transitional tissue that minimizes stress concentrations and allows for load transfer between muscles and skeleton. This unique tissue cannot be reconstructed following injury, leading to high incidence of recurrent failure and stressing the need for new clinical approaches. This review describes the current understanding of the dev...

Biomechanics-driven chondrogenesis: from embryo to adult.

Biomechanics plays a pivotal role in articular cartilage development, pathophysiology, and regeneration. During embryogenesis and cartilage maturation, mechanical stimuli promote chondrogenesis and limb formation. Mechanical loading, which has been characterized using computer modeling and in vivo studies, is crucial for maintaining the phenotype of cartilage. However, excessive or insufficient...